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Nonarteritic anterior ischemic optic neuropathy (NAION) is another ocular disease that often presents with a sudden onset of painless monocular visual loss with altitudinal visual field defects

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This reaction is catalyzed by members of the persulfide dioxygenase (PDO) superfamily, which includes the mitochondrial ethylmalonic encephalopathy protein 1 (ETHE1), genetic inactivation of which leads to embryonic lethality in humans 21